Mycophenolate Mofetil (MMF)-Induced Colitis

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Chronic diarrhoea from mycophenolate mofetil-induced colitis.

1 of 2 DESCRIPTION A 25-year-old female with mixed connective tissue disease (MCTD) complicated by scleroderma renal crisis presented with a 2-week history of profuse, watery diarrhoea that persisted through the night and with fasting. She has been maintained on mycophenolate mofetil (MMF) at 1000 mg/day for 1 year for her MCTD. The patient reported no recent travel or similar illness in her ho...

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Mycophenolate Mofetil-Induced Segmental Colitis Mimicking Ischemic Colitis

Mycophenolate mofetil (MMF) is a commonly used drug in the prevention of allograft rejection in patients with solid organ transplants. Although diffuse colitis has been described in MMF-related colitis, segmental colitis has not been reported. We report the case of a 64-year-old male on MMF therapy who presented for evaluation of afebrile diarrhea and abdominal pain. Flexible sigmoidoscopy reve...

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Mycophenolate mofetil (MMF) in the treatment of epidermolysis bullosa acquisita (EBA) long-term follow-up

E pidermolysis bullosa acquisita (EBA) is an autoimmune mucocutaneous blistering disease. Cutaneous involvement presents with blisters primarily on trauma-prone areas healing with milia. Mucosal involvement can lead to irreversible scarring. The treatment of EBA is based on anecdotal reports in the literature with systemic therapies. Mycophenolate mofetil (MMF) is an immunesuppressing agent tha...

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BENEFICIAL EFFECT OF LOW DOSE CYCLOSPORINE WITH MMF (MYCOPHENOLATE MOFETIL) IN RENAL ALLOGRAFT RECIPIENTS

Background: Calcineurin inhibitors (CNI) have significantly reduced the incidence of acute rejection. Nephrotoxicity however may contribute to long-term allograft dysfunction. Mycophenolate mofetil (MMF) may allow cyclosporine (CsA) dose reduction without increasing the risk of rejection. Methods: In seventy-eight living unrelated kidney transplant patients with renal dysfunction, we studi...

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Physical and Chemical Stability of Mycophenolate Mofetil (MMF) Suspension Prepared at the Hospital

To evaluate the physical and chemical stability of a suspension of mycophenolate mofetil (MMF) prepared in the hospital from commercially available MMF capsules and tablets. Extemporaneous pharmacy was used as a feasible method in this experimental study to prepare suspension form of MMF. Suspension formulations were prepared from both tablets and capsules forms of MMF. Thereafter the stability...

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ژورنال

عنوان ژورنال: Blood

سال: 2016

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v128.22.4795.4795